By III, Joseph W. St. Geme
This booklet describes the starting to be physique of knowledge at the epidemiology, medical manifestations, transmission, pathogenesis, prognosis, and remedy of Kingella kingae infections in little ones. additionally, it covers experimental tools which were built to check the microbiology, genetics, and virulence elements of K. kingae, info that offers the root for brand new ways to therapy and prevention of K. kingae disease. With this content material in brain, excerpts from the e-book can be of relevance for clinicians who take care of pediatric sufferers, for medical microbiologists who're concerned about detecting organisms in medical specimens, and for scientists who're learning K. kingae in an attempt to enhance novel goals for antimicrobial treatment and new ways to prevention.
First remoted within the Nineteen Sixties by way of Elizabeth O. King, a bacteriologist on the CDC, Kingella kingae was mostly overlooked over the subsequent twenty years as a human pathogen as a result of its unusual restoration from sufferers with disorder. despite the fact that, in fresh years K. kingae has been more and more well-known as a clinically very important pathogen in young ones, and is presently famous because the best reason behind osteoarticular infections in childrens in an increasing number of international locations. examine into this organism has grown significantly during the last 15 years, leading to a greater appreciation of the significance of K. kingae in pediatric sufferers and of the molecular mechanisms of disease.
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